Clinical Chemistry for Developing Countries: Mass Spectrometry.

ABSTRACT: Early disease diagnosis is necessary to enable timely interventions. Implementation of this vital task in the developing world is challenging owing to limited resources. Diagnostic approaches developed for resource-limited settings have often involved colorimetric tests (based on immunoassays) due to their low cost. Unfortunately, the performance/sensitivity of such simplistic tests are often limited and significantly hinder opportunities for early disease detection. A new criterion for selecting diagnostic tests in low- and middle-income countries is proposed here that is based on performance-to-cost ratio. For example, modern mass spectrometry (MS) now involves analysis of the native sample in the open laboratory environment, enabling applications in many fields, including clinical resea

SUBMITTER: Lee S 

PROVIDER: S-EPMC8932337 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature