Characterising spatial patterns of neglected tropical disease transmission using integrated sero-surveillance in Northern Ghana.

ABSTRACT:

Background

As prevalence decreases in pre-elimination settings, identifying the spatial distribution of remaining infections to target control measures becomes increasingly challenging. By measuring multiple antibody responses indicative of past exposure to different pathogens, integrated serological surveys enable simultaneous characterisation of residual transmission of multiple pathogens.

Methodology/principal findings

Here, we combine integrated serological surveys with geostatistical modelling and remote sensing-derived environmental data to estimate the spatial distribution of exposure to multiple diseases in children in Northern Ghana. The study utilised the trachoma surveillance survey platform (cross-sectional two-stage cluster-sampled surveys) to collect informatio

SUBMITTER: Fornace KM 

PROVIDER: S-EPMC8932554 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature