Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC8933278 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Zhang Xiaochao X Hu Yabing Y Pan Yonglong Y Xiong Yixiao Y Zhang Yuxin Y Han Mengzhen M Dong Keshuai K Song Jia J Liang Huifang H Ding Zeyang Z Zhang Xuewu X Zhu He H Liu Qiumeng Q Lu Xun X Feng Yongdong Y Chen Xiaoping X Zhang Zhanguo Z Zhang Bixiang B
Oncogene 20220209 12
Discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family, and its ligand is collagen. Previous studies demonstrated that DDR1 is highly expressed in many tumors. However, its role in hepatocellular carcinoma (HCC) remains obscure. In this study, we found that DDR1 was upregulated in HCC tissues, and the expression of DDR1 in TNM stage II-IV was higher than that in TNM stage I in HCC tissues, and high DDR1 expression was associated with poor prognosis. Gene expression ...[more]