Prognosis Comparison Between Nipple-Sparing Mastectomy and Total Mastectomy in Breast Cancer: A Case-Control Study After Propensity Score Matching.

ABSTRACT:

Background

Currently, the operation rate of nipple-sparing mastectomy (NSM) is increasing. However, the long-term prognosis of NSM is not well documented. We utilized the Surveillance, Epidemiology, and End Results (SEER) database to analyze the long-term prognosis of NSM compared with total mastectomy (TM).

Methods

Population-level data of female breast cancer patients treated with NSM and TM were extracted from 1998 to 2016 from the SEER database. Propensity score matching (PSM) was performed to reduce the influence of selection bias and confounding variables in comparisons. Kaplan-Meier analysis, log-rank test, and Cox proportional hazard regression were performed.

Results

A total of 5765 patients underwent NSM, which increased from 266 in 2004-2009 to 5370 in 2010

SUBMITTER: Fu M 

PROVIDER: S-EPMC8933300 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature