Clinical validation of a spectroscopic liquid biopsy for earlier detection of brain cancer.

ABSTRACT:

Background

Diagnostic delays impact the quality of life and survival of patients with brain tumors. Earlier and expeditious diagnoses in these patients are crucial to reduce the morbidities and mortalities associated with brain tumors. A simple, rapid blood test that can be administered easily in a primary care setting to efficiently identify symptomatic patients who are most likely to have a brain tumor would enable quicker referral to brain imaging for those who need it most.

Methods

Blood serum samples from 603 patients were prospectively collected and analyzed. Patients either had non-specific symptoms that could be indicative of a brain tumor on presentation to the Emergency Department, or a new brain tumor diagnosis and referral to the neurosurgical unit, NHS Lothian,

SUBMITTER: Cameron JM 

PROVIDER: S-EPMC8934542 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature