MicroCT Can Characterize Clots Retrieved With Mechanical Thrombectomy From Acute Ischemic Stroke Patients-A Preliminary Report.

ABSTRACT:

Background

Characterization of the clot occluding the arteries in acute ischemic stroke received ample attention, in terms of elucidating the relationship between the clot composition, its etiology and its amenability for pharmacological treatment and mechanical thrombectomy approaches. Traditional analytical techniques such as conventional 2D histopathology or electron microscopy sample only small parts of the clot. Visualization and analysis in 3D are necessary to depict and comprehend the overall organization of the clot. The aim of this study is to investigate the potential of microCT for characterizing the clot composition, structure, and organization.

Methods

In a pilot study, we analyzed with microCT clots retrieved from 14 patients with acute ischemic stroke. The fol

SUBMITTER: Dumitriu LaGrange D 

PROVIDER: S-EPMC8934771 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature