Right atrial pressure represents cumulative cardiac burden in heart failure with preserved ejection fraction.

ABSTRACT:

Aims

Right-sided filling pressure is elevated in some patients with heart failure (HF) and preserved ejection fraction (HFpEF). We hypothesized that right atrial pressure (RAP) would represent the cumulative burden of abnormalities in the left heart, pulmonary vasculature, and the right heart.

Methods and results

Echocardiography was performed in 399 patients with HFpEF. RAP was estimated from inferior vena cava morphology and its respiratory change [estimated right atrial pressure (eRAP)], and patients were divided according to eRAP (3 or ≥8 mmHg). Patients with higher eRAP displayed more severe abnormalities in LV diastolic function as well as right heart structure and function than those with normal eRAP. Cardiac deaths or HF hospitalization occurred in 84 patients over a

SUBMITTER: Nagata R 

PROVIDER: S-EPMC8934927 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature