Myocardial strain to identify benefit from beta-blockers in patients with heart failure with reduced ejection fraction.

ABSTRACT:

Aims

Not all patients with heart failure with reduced ejection fraction (HFrEF) benefit equally from beta-blockers. Previous studies suggest that myocardial strain that reflects myocardial deformation may have a better prognostic value than the left ventricular ejection fraction. We aimed to evaluate the differential effect of beta-blockers according to the global longitudinal strain (GLS) in patients with HFrEF.

Methods and results

Of the 4312 patients in the Strain for Risk Assessment and Therapeutic Strategies in Patients with Acute Heart Failure registry, we included 2126 HFrEF patients whose data on beta-blocker use and GLS were available. Patients were categorized into two groups: one group of patients had GLS ≥ 10%, and the other group had GLS < 10%. The primary outco

SUBMITTER: Park CS 

PROVIDER: S-EPMC8934950 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature