Diffusion spectrum imaging predicts hippocampal sclerosis in mesial temporal lobe epilepsy patients.

ABSTRACT:

Objectives

Epileptic patients suffer from seizure recurrence after surgery due to the challenging localization. Improvement of the noninvasive imaging-based approach for a better definition of the abnormalities would be helpful for a better outcome.

Methods

The quantitative anisotropy (QA) of diffusion spectrum imaging (DSI) is a quantitative scalar of evaluating the water diffusivity. Herein, we investigated the association between neuronal diameters or density acquired in literature and QA of DSI as well as the seizure localization in temporal lobe epilepsy. Thirty healthy controls (HCs) and 30 patients with hippocampal sclerosis (HS) were retrospectively analyzed. QA values were calculated and interactively compared between the areas with different neuronal diameter/densi

SUBMITTER: Wang ZM 

PROVIDER: S-EPMC8935311 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature