Estimating Neonatal Herpes Simplex Virus Incidence and Mortality Using Capture-recapture, Florida.

ABSTRACT:

Background

Neonatal herpes simplex virus infection (nHSV) leads to severe morbidity and mortality, but national incidence is uncertain. Florida regulations require that healthcare providers report cases, and clinical laboratories report test results when herpes simplex virus (HSV) is detected. We estimated nHSV incidence using laboratory-confirmed provider-reported cases and electronic laboratory reports (ELR) stored separately from provider-reported cases. Mortality was estimated using provider-reported cases, ELR, and vital statistics death records.

Methods

For 2011-2017, we reviewed: provider-reported cases (infants ≤ 60 days of age with HSV infection confirmed by culture or polymerase chain reaction [PCR]), ELR of HSV-positive culture or PCR results in the same age group

SUBMITTER: Matthias J 

PROVIDER: S-EPMC8935354 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature