Urinary metabolomics reveals the biological characteristics of early pregnancy in pigs.

ABSTRACT:

Background

Embryo implantation in sows is an important event during pregnancy. During this process, blastocysts undergo dramatic morphologic changes, and the endometrium becomes receptive. Studies have shown that developmental changes associated with the crosstalk between peri-implantation embryos and embryo-uterine are driven by various biomolecules secreted by the endometrium and embryos. In sows, changes in the uterus are also reflected in circulating body fluids and urine. Metabolomics reveals the metabolic state of cells, tissues, and organisms. In this study, we collected urine samples from large white sows during the peri-implantation period. The levels of urinary metabolites at different periods were analyzed using ultra-performance liquid chromatography/tandem mass spectro

SUBMITTER: Zhou C 

PROVIDER: S-EPMC8935750 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature