Elevated Plasma Thymic Stromal Lymphopoietin After Acute Myocardial Infarction.

ABSTRACT:

Background

Thymic stromal lymphopoietin (TSLP), a distant paralog of the cytokine IL-7, has been shown to be associated with atherosclerosis. However, the effect of plasma TSLP level after acute myocardial infarction (AMI) remains largely unclear. Thus, we aimed to assess the relationship between the concentration of TSLP at admission and the risk of major adverse cardiovascular events (MACE) in AMI patients.

Methods

A total of 175 patients with AMI and 145 unstable angina (UA) controls were recruited in the present study. The clinical characteristics were collected, and MACE was recorded during hospitalization and the follow-up period after discharge.

Results

The median value (25, 75 percentiles) of TSLP concentrations in the AMI group was higher than that in the UA

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC8936131 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature