Host and geographic barriers shape the competition, coexistence, and extinction patterns of influenza A (H1N1) viruses.

ABSTRACT: The influenza virus mutates and spreads rapidly, making it suitable for studying evolutionary and ecological processes. The ecological factors and processes by which different lineages of influenza compete or coexist within hosts through time and across geographical space are poorly known. We hypothesized that competition would be stronger for influenza viruses infecting the same host compared to different hosts (the Host Barrier Hypothesis), and for those with a higher cross-region transmission intensity (the Geographic Barrier Hypothesis). Using available sequences of the influenza A (H1N1) virus in GenBank, we identified six lineages, twelve clades, and several replacement events. We found that human-hosted lineages had a higher cross-region transmission intensity than swine-hosted line

SUBMITTER: Cheng C 

PROVIDER: S-EPMC8938227 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature