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Biomarkers common for inflammatory periodontal disease and depression: A systematic review.


ABSTRACT:

Background

Dysregulated immune response arising in the periphery can induce depressive symptoms through neuroimmune interactions. Inflammatory oral pathology can be a potent inducer of chronic neuroimmune response relevant to depression. We aimed to synthesize available evidence for the association between inflammatory periodontal diseases (IPD) and major depression (MD) in relation to a broad range of biomarkers.

Methods

Medline, Embase, PsycInfo, Cochrane Library, Web of Science and Scopus databases were searched from inception until January 27, 2022. Search terms included subject headings and synonyms for inflammatory periodontal disease and depression. Studies that reported data on both depression and inflammatory periodontal disease as categories along with measurement

SUBMITTER: Neupane SP 

PROVIDER: S-EPMC8938251 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature