Does conflict of interest affect the reported fusion rates of bone graft substitutes and extenders?

ABSTRACT:

Background

Bone graft extenders are being used more in spine surgery as a substitute for iliac crest bone graft. However, potential conflict of interest could impact average fusion rates. The purpose of this study was to evaluate whether fusion rates reported in the literature were different in papers evaluating bone graft substitutes and extenders when there was potential conflict of interest versus no potential conflict of interest.

Methods

Pubmed was searched for studies evaluating fusion rates when bone graft extenders including demineralized bone matrix, hydroxyapatite, and tricalcium sulfate were used. Studies were screened for one or two level fusions and for degenerative spinal conditions. The average fusion rates of subgroups were compared using unpaired Student's t

SUBMITTER: Chin G 

PROVIDER: S-EPMC8938602 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature