Evaluation of shoseiryuto for seasonal allergic rhinitis, using an environmental challenge chamber.

ABSTRACT:

Background

Complementary and alternative medicine, including Japanese traditional medicine (JTM), has been used for various allergic diseases, but the evidence is limited. Shoseiryuto (Xiao-Qing-Long-Tang), one of the representative JTM drugs, is frequently used to treat allergic rhinitis (AR). However, its efficacy for seasonal AR has not been fully established. Using an Environmental challenge chamber (ECC), we evaluated the therapeutic effects of shoseiryuto on AR induced by Japanese cedar pollen (JCP).

Methods

A placebo-controlled double-blind crossover study with shoseiryuto was conducted using the ECC. The shoseiryuto or placebo was orally administered from 2 weeks before the exposure test. The pollen exposure test was conducted for 3 h, and the pollen concentration wa

SUBMITTER: Kurita J 

PROVIDER: S-EPMC8938619 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature