Simulating the Genetics Clinic of the Future - whether undergoing whole-genome sequencing shapes professional attitudes.

ABSTRACT: Whole-genome sequencing (WGS) can provide valuable health insight for research participants or patients. Opportunities to be sequenced are increasing as direct-to-consumer (DTC) testing becomes more prevalent, but it is still fairly unusual to have been sequenced. We offered WGS to fourteen professionals with pre-existing familiarity with an interest in human genetics - healthcare, science, policy and art. Participants received a hard drive containing their personal sequence data files (.BAM,.gvcf), without further explanation or obligation, to consider how experiencing WGS firsthand might influence their professional attitudes. We performed semi-structured pre- and post-sequencing interviews with each participant to identify key themes that they raised after being sequenced. To evaluate h

SUBMITTER: Brunfeldt M 

PROVIDER: S-EPMC8941039 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature