A green protocol for the electrochemical synthesis of a fluorescent dye with antibacterial activity from imipramine oxidation.

ABSTRACT: Electrochemical oxidation of imipramine (IMP) has been studied in aqueous solutions by cyclic voltammetry and controlled-potential coulometry techniques. Our voltammetric results show a complex behavior for oxidation of IMP at different pH values. In this study, we focused our attention on the electrochemical oxidation of IMP at a pH of about 5. Under these conditions, our results show that the oxidation of IMP leads to the formation of a unique dimer of IMP (DIMP). The structure of synthesized dimer is fully characterized by UV-visible, FTIR, ¹H NMR, ¹³C NMR and mass spectrometry techniques. It seems that the first step in the oxidation of IMP is the cleavage of the alkyl group (formation of IMPH). After this, a domino oxidation-hydroxylation-dimerization-oxidation r

SUBMITTER: Souri Z 

PROVIDER: S-EPMC8941072 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature