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High-precision neural stimulation through optoacoustic emitters.


ABSTRACT: Neuromodulation poses an invaluable role in deciphering neural circuits and exploring clinical treatment of neurological diseases. Optoacoustic neuromodulation is an emerging modality benefiting from the merits of ultrasound with high penetration depth as well as the merits of photons with high spatial precision. We summarize recent development in a variety of optoacoustic platforms for neural modulation, including fiber, film, and nanotransducer-based devices, highlighting the key advantages of each platform. The possible mechanisms and main barriers for optoacoustics as a viable neuromodulation tool are discussed. Future directions in fundamental and translational research are proposed.

SUBMITTER: Shi L 

PROVIDER: S-EPMC8941197 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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High-precision neural stimulation through optoacoustic emitters.

Shi Linli L   Jiang Ying Y   Zheng Nan N   Cheng Ji-Xin JX   Yang Chen C  

Neurophotonics 20220323 3


Neuromodulation poses an invaluable role in deciphering neural circuits and exploring clinical treatment of neurological diseases. Optoacoustic neuromodulation is an emerging modality benefiting from the merits of ultrasound with high penetration depth as well as the merits of photons with high spatial precision. We summarize recent development in a variety of optoacoustic platforms for neural modulation, including fiber, film, and nanotransducer-based devices, highlighting the key advantages of  ...[more]

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