Comparative genomics and evolutionary analysis of Lactococcus garvieae isolated from human endocarditis.

ABSTRACT: Lactococcus garvieae is a well-known pathogen of fish, but is rarely involved in infections in humans and other mammals. In humans, the main clinical manifestation of L. garvieae infections is endocarditis usually related to the ingestion of contaminated food, such as undercooked fish and shellfish. This study presents the first complete genomic sequence of a clinical L. garvieae strain isolated from a patient with endocarditis and its comparative analysis with other genomes. This human isolate contains a circular chromosome of 2 099 060 bp and one plasmid of 50 557 bp. In comparison with other fully sequenced L. garvieae strains, the chromosomal DNA of L. garvieae Lg-Granada carries a low proportion of insertion sequence elements and a higher number of p

SUBMITTER: Frances-Cuesta C 

PROVIDER: S-EPMC8942021 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature