Unveiling the genomic potential of Pseudomonas type strains for discovering new natural products.

ABSTRACT: Microbes host a huge variety of biosynthetic gene clusters that produce an immeasurable array of secondary metabolites with many different biological activities such as antimicrobial, anticarcinogenic and antiviral. Despite the complex task of isolating and characterizing novel natural products, microbial genomic strategies can be useful for carrying out these types of studies. However, although genomic-based research on secondary metabolism is on the increase, there is still a lack of reports focusing specifically on the genus Pseudomonas. In this work, we aimed (i) to unveil the main biosynthetic systems related to secondary metabolism in Pseudomonas type strains, (ii) to study the evolutionary processes that drive the diversification of their coding regions and (iii) to select Pseudomon

SUBMITTER: Saati-Santamaria Z 

PROVIDER: S-EPMC8942027 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature