Relationship between asthma and IL-17 gene polymorphism in a Turkish population.

ABSTRACT:

Background

Asthma is a prevalent chronic obstructive disease of the airways.

Aims

The aim of our study was to investigate the relationship between asthma and IL-17F gene 74488 T > C, IL-17A gene -197G > A, and IL17A gene -737C > T polymorphisms in Turkish population.

Methods

In our study, peripheral blood samples collected from a total of 127 subjects, with 65 in the patient group and 62 in the control group, were analyzed for IL-17F gene 74488 T > C, IL-17A gene -197G > A, and IL17A gene -737C > T polymorphisms using next-generation sequencing.

Results

There was no statistically significant relationship between IL-17A gene -197G > A and IL-17A gene -737C > T polymorphisms and the risk of developing asthma. It was found that the risk of developing asthma was 2.

SUBMITTER: Yuce GD 

PROVIDER: S-EPMC8942807 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature