The ViReflow pipeline enables user friendly large scale viral consensus genome reconstruction.

ABSTRACT: Throughout the COVID-19 pandemic, massive sequencing and data sharing efforts enabled the real-time surveillance of novel SARS-CoV-2 strains throughout the world, the results of which provided public health officials with actionable information to prevent the spread of the virus. However, with great sequencing comes great computation, and while cloud computing platforms bring high-performance computing directly into the hands of all who seek it, optimal design and configuration of a cloud compute cluster requires significant system administration expertise. We developed ViReflow, a user-friendly viral consensus sequence reconstruction pipeline enabling rapid analysis of viral sequence datasets leveraging Amazon Web Services (AWS) cloud compute resources and the Reflow system. ViReflow was

SUBMITTER: Moshiri N 

PROVIDER: S-EPMC8943356 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature