Sputnik V protection from COVID-19 in people living with HIV under antiretroviral therapy.

ABSTRACT:

Background

HIV-infection is known to aggravate the course of many infectious diseases, including COVID-19. International guidance recommends vaccination of HIV+ individuals against SARS-CoV-2. There is a paucity of data on epidemiological efficacy assessment of COVID-19 vaccines among HIV+. This paper provides a preliminary assessment of Sputnik V vaccine effectiveness in HIV+ patients on antiretroviral therapy (ART).

Methods

We performed a retrospective cohort study to assess the effectiveness of the standard Sputnik V vaccination regimen in 24,423 HIV+ Moscow residents during spring - summer 2021, that included dominance of delta variant, with estimation of hospitalization and severe illness rates in vaccinated and unvaccinated patients. Data were extracted from the Moscow

SUBMITTER: Gushchin VA 

PROVIDER: S-EPMC8943473 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature