Manual and automated analysis of atrophy patterns in dementia with Lewy bodies on MRI.

ABSTRACT:

Background

Dementia with Lewy bodies (DLB) is the second most common dementia type in patients older than 65 years. Its atrophy patterns remain unknown. Its similarities to Parkinson's disease and differences from Alzheimer's disease are subjects of current research.

Methods

The aim of our study was (i) to form a group of patients with DLB (and a control group) and create a 3D MRI data set (ii) to volumetrically analyze the entire brain in these groups, (iii) to evaluate visual and manual metric measurements of the innominate substance for real-time diagnosis, and (iv) to compare our groups and results with the latest literature. We identified 102 patients with diagnosed DLB in our psychiatric and neurophysiological archives. After exclusion, 63 patients with valid 3D data s

SUBMITTER: Khadhraoui E 

PROVIDER: S-EPMC8943955 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature