Modelling new insecticide-treated bed nets for malaria-vector control: how to strategically manage resistance?

ABSTRACT:

Background

The program to eradicate malaria is at a critical juncture as a new wave of insecticides for mosquito control enter their final stages of development. Previous insecticides have been deployed one-at-a-time until their utility was compromised, without the strategic management of resistance. Recent investment has led to the near-synchronous development of new insecticides, and with it the current opportunity to build resistance management into mosquito-control methods to maximize the chance of eradicating malaria.

Methods

Here, building on the parameter framework of an existing mathematical model, resistance-management strategies using multiple insecticides are compared to suggest how to deploy combinations of available and new insecticides on bed nets to achieve ma

SUBMITTER: Madgwick PG 

PROVIDER: S-EPMC8944051 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature