Review and Comparison of Antimicrobial Resistance Gene Databases.

ABSTRACT: As the prevalence of antimicrobial resistance genes is increasing in microbes, we are facing the return of the pre-antibiotic era. Consecutively, the number of studies concerning antibiotic resistance and its spread in the environment is rapidly growing. Next generation sequencing technologies are widespread used in many areas of biological research and antibiotic resistance is no exception. For the rapid annotation of whole genome sequencing and metagenomic results considering antibiotic resistance, several tools and data resources were developed. These databases, however, can differ fundamentally in the number and type of genes and resistance determinants they comprise. Furthermore, the annotation structure and metadata stored in these resources can also contribute to their differences.

SUBMITTER: Papp M 

PROVIDER: S-EPMC8944830 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature