American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation.

ABSTRACT:

Background

Sickle cell disease (SCD) is a life-limiting inherited hemoglobinopathy that results in significant complications and affects quality of life. Hematopoietic stem cell transplantation (HSCT) is currently the only curative intervention for SCD; however, guidelines are needed to inform how to apply HSCT in clinical practice.

Objective

These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and health professionals in their decisions about HSCT for SCD.

Methods

The multidisciplinary guideline panel formed by ASH included 2 patient representatives and was balanced to minimize potential bias from conflicts of interest. The Mayo Evidence-Based Practice Research Program supported the guideline develo

SUBMITTER: Kanter J 

PROVIDER: S-EPMC8945587 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature