Cell Retention as a Viable Strategy for PHA Production from Diluted VFAs with Bacillus megaterium.

ABSTRACT: The production of biodegradable and biocompatible materials such as polyhydroxyalkanoates (PHAs) from waste-derived volatile fatty acids (VFAs) is a promising approach towards implementing a circular bioeconomy. However, VFA solutions obtained via acidification of organic wastes are usually too diluted for direct use in standard batch or fed-batch processes. To overcome these constraints, this study introduces a cell recycle fed-batch system using Bacillus megaterium uyuni S29 for poly(3-hydroxybutyrate) (P3HB) production from acetic acid. The concentrations of dry cell weight (DCW), P3HB, acetate, as well as nitrogen as the limiting substrate component, were monitored during the process. The produced polymer was characterized in terms of molecular weight and thermal properties after extra

SUBMITTER: Kacanski M 

PROVIDER: S-EPMC8945770 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature