Stroke Genomics: Current Knowledge, Clinical Applications and Future Possibilities.

ABSTRACT: The pathophysiology of stoke involves many complex pathways and risk factors. Though there are several ongoing studies on stroke, treatment options are limited, and the prevalence of stroke is continuing to increase. Understanding the genomic variants and biological pathways associated with stroke could offer novel therapeutic alternatives in terms of drug targets and receptor modulations for newer treatment methods. It is challenging to identify individual causative mutations in a single gene because many alleles are responsible for minor effects. Therefore, multiple factorial analyses using single nucleotide polymorphisms (SNPs) could be used to gain new insight by identifying potential genetic risk factors. There are many studies, such as Genome-Wide Association Studies (GWAS) and Pheno

SUBMITTER: Appunni S 

PROVIDER: S-EPMC8946102 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature