Functional Integration and Segregation in a Multilayer Network Model of Patients with Schizophrenia.

ABSTRACT: Research has shown that abnormal brain networks in patients with schizophrenia appear at different frequencies, but the relationship between these different frequencies is unclear. Therefore, it is necessary to use a multilayer network model to evaluate the integration of information from different frequency bands. To explore the mechanism of integration and separation in the multilayer network of schizophrenia, we constructed multilayer frequency brain network models in 50 patients with schizophrenia and 69 healthy subjects, and the entropy of the multiplex degree (EMD) and multilayer clustering coefficient (MCC) were calculated. The results showed that the ability to integrate and separate information in the multilayer network of patients was significantly higher than that of normal peop

SUBMITTER: Wei J 

PROVIDER: S-EPMC8946586 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature