Identification of Genetically Related HCV Infections Among Self-Described Injecting Partnerships.

ABSTRACT:

Background

The current opioid epidemic across the United States has fueled a surge in the rate of new hepatitis C virus (HCV) infections among young persons who inject drugs (PWIDs). Paramount to interrupting transmission is targeting these high-risk populations and understanding the underlying network structures facilitating transmission within these communities.

Methods

Deep sequencing data were obtained for 52 participants from 32 injecting partnerships enrolled in the U-Find-Out (UFO) Partner Study, which is a prospective study of self-described injecting dyad partnerships from a large community-based study of HCV infection in young adult PWIDs from San Francisco. Phylogenetically linked transmission events were identified using traditional genetic-distance measures and

SUBMITTER: Tully DC 

PROVIDER: S-EPMC8946742 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature