Functional Role of microRNAs in Regulating Cardiomyocyte Death.

ABSTRACT: microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein, we present an updated and comprehensive overview of the functional involvement of miRs in the regulation of cardiomyocyte death, a central event in acute myocardial infarction, ischemia/reperfusion, and heart failure. Specifically, in this systematic review we are focusing on necrosis, apoptosis, and autophagy.

SUBMITTER: Kansakar U 

PROVIDER: S-EPMC8946783 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature