Prevention of gestational diabetes in pregnant women with obesity: protocol for a pilot randomised controlled trial.

ABSTRACT:

Background

Obesity in pregnancy increases the risk of gestational diabetes mellitus (GDM) and associated adverse outcomes. Despite metabolic differences, all pregnant women with obesity are considered to have the same risk of developing GDM. Improved risk stratification is required to enable targeted intervention in women with obesity who would benefit the most. The aim of this study is to identify pregnant women with obesity at higher risk of developing GDM and, in a pilot randomised controlled trial (RCT), test feasibility and assess the efficacy of a lifestyle intervention and/or metformin to improve glycaemic control.

Methods

Women aged 18 years or older with a singleton pregnancy and body mass index (BMI) ≥ 30kg/m² will be recruited from one maternity unit in

SUBMITTER: Quotah OF 

PROVIDER: S-EPMC8948450 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature