Examination of preliminary behavioral and effective connectivity findings from treatment response to citalopram in cocaine use disorder: A dynamic causal modeling study.
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ABSTRACT:
SUBMITTER: Snyder AD
PROVIDER: S-EPMC8948471 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Examination of preliminary behavioral and effective connectivity findings from treatment response to citalopram in cocaine use disorder: A dynamic causal modeling study.
Snyder A D AD Zuniga E E Ma L L Steinberg J L JL Woisard K K Narayana P A PA Lane S S Schmitz J J Moeller F G FG
Psychiatry research. Neuroimaging 20200615
We sought effective (directional) connectivity parameters associated with response to citalopram in cocaine use disorder (CUD) by conducting a functional magnetic resonance imaging (fMRI) experiment with participants diagnosed with CUD (n = 13) and matched healthy controls (HC; n = 17). CUD participants showed a positive correlation between bilateral DLPFC-to-putamen effective connectivity and treatment effectiveness score. These preliminary results support further investigation of prefrontal-st ...[more]
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