Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19.

ABSTRACT:

Importance

Prior observational studies suggest that aspirin use may be associated with reduced mortality in high-risk hospitalized patients with COVID-19, but aspirin's efficacy in patients with moderate COVID-19 is not well studied.

Objective

To assess whether early aspirin use is associated with lower odds of in-hospital mortality in patients with moderate COVID-19.

Design, setting, and participants

Observational cohort study of 112 269 hospitalized patients with moderate COVID-19, enrolled from January 1, 2020, through September 10, 2021, at 64 health systems in the United States participating in the National Institute of Health's National COVID Cohort Collaborative (N3C).

Exposure

Aspirin use within the first day of hospitalization.

Main outcome and meas

SUBMITTER: Chow JH 

PROVIDER: S-EPMC8948531 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature