Amperometric Monitoring of Dissolution of pH-Responsive EUDRAGIT® Polymer Film Coatings.

ABSTRACT: Electrochemical sensors are powerful tools for the detection and real-time monitoring of a wide variety of analytes. However, the long-term operation of Faradaic sensors in complex media is challenging due to fouling. The protection of the electrode surface during in vivo operation is a key element for improving the monitoring of analytes. Here, we study different EUDRAGIT® controlled release acrylate copolymers for protecting electrode surfaces. The dissolution of these polymers-namely EUDRAGIT® L 30 D-55 and EUDRAGIT® FS 30 D-is triggered by a change in pH of the environment, and it is electrochemically monitored by detecting electrode access by means of a redox probe. The full dissolution of the polymer is achieved within 30 min and the electrode response indicates a complete recovery o

SUBMITTER: Mestres J 

PROVIDER: S-EPMC8949041 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature