Ontology highlight
ABSTRACT:
SUBMITTER: Yu P
PROVIDER: S-EPMC8949104 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Yu Pengfei P Chen Zhenshan Z Liu Yuecheng Y Gu Zhengwei Z Wang Xiaoming X Zhang Yaowen Y Ma Yanni Y Dong Meiyue M Tian Zhenhua Z
Molecules (Basel, Switzerland) 20220321 6
As an important source of cholinesterase inhibitors, alkaloids in natural products have high potential value in terms of exerting pharmacological activities. In this study, a strategy for targeted preparation of cholinesterase inhibitors in <i>Uncaria rhynchophlly</i> (Miq.) Miq. ex Havil (UR) by high-speed counter-current chromatography was provided. In the method, a two-phase polar solvent system composed of ethyl acetate/<i>n</i>-butanol/water (1:4:5, <i>v</i>/<i>v</i>/<i>v</i>) was used, whi ...[more]