Real-World Impact of a Pharmacogenomics-Enriched Comprehensive Medication Management Program.

ABSTRACT: The availability of clinical decision support systems (CDSS) and other methods for personalizing medicine now allows evaluation of their real-world impact on healthcare delivery. For example, addressing issues associated with polypharmacy in older patients using pharmacogenomics (PGx) and comprehensive medication management (CMM) is thought to hold great promise for meaningful improvements across the goals of the Quadruple Aim. However, few studies testing these tools at scale, using relevant system-wide metrics, and under real-world conditions, have been published to date. Here, we document a reduction of ~$7000 per patient in direct medical charges (a total of $37 million over 5288 enrollees compared to 22,357 non-enrolled) in Medicare Advantage patients (≥65 years) receiving benefits th

SUBMITTER: Jarvis JP 

PROVIDER: S-EPMC8949247 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature