Quantitative assessment of retinal fluid in neovascular age-related macular degeneration under anti-VEGF therapy.

ABSTRACT: The retinal world has been revolutionized by optical coherence tomography (OCT) and anti-vascular endothelial growth factor (VEGF) therapy. The numbers of intravitreal injections are on a constant rise and management in neovascular age-related macular degeneration (nAMD) is mainly driven by the qualitative assessment of macular fluid as detected on OCT scans. The presence of macular fluid, particularly subretinal fluid (SRF) and intraretinal fluid (IRF), has been used to trigger re-treatments in clinical trials and the real world. However, large discrepancies can be found between the evaluations of different readers or experts and especially small amounts of macular fluid might be missed during this process. Pixel-wise detection of macular fluid uses an entire OCT volume to calculate exact

SUBMITTER: Reiter GS 

PROVIDER: S-EPMC8949734 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature