Molecular Processes in Stress Urinary Incontinence: A Systematic Review of Human and Animal Studies.

ABSTRACT: Stress urinary incontinence (SUI) is a common and burdensome condition. Because of the large knowledge gap around the molecular processes involved in its pathophysiology, the aim of this review was to provide a systematic overview of genetic variants, gene and protein expression changes related to SUI in human and animal studies. On 5 January 2021, a systematic search was performed in Pubmed, Embase, Web of Science, and the Cochrane library. The screening process and quality assessment were performed in duplicate, using predefined inclusion criteria and different quality assessment tools for human and animal studies respectively. The extracted data were grouped in themes per outcome measure, according to their functions in cellular processes, and synthesized in a narrative review. Finally,

SUBMITTER: Post WM 

PROVIDER: S-EPMC8949972 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature