Genetic Predisposition to Schizophrenia and Depressive Disorder Comorbidity.

ABSTRACT: Background: Patients with schizophrenia have an increased risk of depressive disorders compared to the general population. The comorbidity between schizophrenia and depression suggests a potential coincidence of the pathophysiology and/or genetic predictors of these mental disorders. The aim of this study was to review the potential genetic predictors of schizophrenia and depression comorbidity. Materials and Methods: We carried out research and analysis of publications in the databases PubMed, Springer, Wiley Online Library, Taylor & Francis Online, Science Direct, and eLIBRARY.RU using keywords and their combinations. The search depth was the last 10 years (2010-2020). Full-text original articles, reviews, meta-analyses, and clinical observations were analyzed. A total of 459 articles we

SUBMITTER: Shnayder NA 

PROVIDER: S-EPMC8950769 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature