Aspects of Biological Replication and Evolution Independent of the Central Dogma: Insights from Protein-Free Vesicular Transformations and Protein-Mediated Membrane Remodeling.

ABSTRACT: Biological membrane remodeling is central to living systems. In spite of serving as "containers" of whole-living systems and functioning as dynamic compartments within living systems, biological membranes still find a "blue collar" treatment compared to the "white collar" nucleic acids and proteins in biology. This may be attributable to the fact that scientific literature on biological membrane remodeling is only 50 years old compared to ~ 150 years of literature on proteins and a little less than 100 years on nucleic acids. However, recently, evidence for symbiotic origins of eukaryotic cells from data only on biological membranes was reported. This, coupled with appreciation of reproducible amphiphilic self-assemblies in aqueous environments (mimicking replication), has already initiate

SUBMITTER: Mittal A 

PROVIDER: S-EPMC8951669 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature