Exposure to Antineoplastic Drugs in Occupational Settings: A Systematic Review of Biological Monitoring Data.

ABSTRACT: The high toxicity of antineoplastic drugs (ADs) makes them dangerous not only for patients, but also for exposed workers. Therefore, the aim of this review was to provide an updated overview of the biological monitoring of occupational AD exposure in order to extrapolate information useful to improve risk assessment and management strategies in workplaces. Several studies demonstrated that remarkable portions of healthcare workers may have traces of these substances or their metabolites in biological fluids, although with some conflicting results. Nurses, directly engaged in AD handling, were the occupational category at higher risk of contamination, although, in some cases, personnel not involved in AD-related tasks also showed quantifiable internal doses. Overall, further research carrie

SUBMITTER: Leso V 

PROVIDER: S-EPMC8952240 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature