Adherence and Persistence to Biological Drugs for Psoriasis: Systematic Review with Meta-Analysis.

ABSTRACT: Despite the large number of biologics currently available for moderate-to-severe psoriasis, poor adherence and persistence to therapy represent the main issues for both the clinical and economic management of psoriasis. However, the data about adherence and persistence to biologics in psoriasis patients are conflicting. Our aim was to produce summary estimates of adherence and persistence to biologics in adult patients with psoriasis. We performed a systematic review and meta-analysis of observational studies, searching two databases (PubMed and Embase). Sixty-two records met the inclusion criteria, and a meta-analysis was conducted on fifty-five studies. Overall, the proportion of adherent and persistent patients to biological therapy was 0.61 (95% confidence interval: 0.48-0.73) and 0.63

SUBMITTER: Piragine E 

PROVIDER: S-EPMC8953825 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature