Clinical and Molecular Relationships between COVID-19 and Feline Infectious Peritonitis (FIP).

ABSTRACT: The emergence of severe acute respiratory syndrome 2 (SARS-CoV-2) has led the medical and scientific community to address questions surrounding the pathogenesis and clinical presentation of COVID-19; however, relevant clinical models outside of humans are still lacking. In felines, a ubiquitous coronavirus, described as feline coronavirus (FCoV), can present as feline infectious peritonitis (FIP)-a leading cause of mortality in young cats that is characterized as a severe, systemic inflammation. The diverse extrapulmonary signs of FIP and rapidly progressive disease course, coupled with a closely related etiologic agent, present a degree of overlap with COVID-19. This paper will explore the molecular and clinical relationships between FIP and COVID-19. While key differences between the two

SUBMITTER: Sweet AN 

PROVIDER: S-EPMC8954060 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature