Pentachlorophenol has significant adverse effects on hematopoietic and immune system development in zebrafish (Danio rerio).

ABSTRACT: In November 2018, the Camp Fire devastated the mountain community of Paradise, CA. The burning of plastic pipes, wiring, construction materials, paint, and car batteries released toxic chemicals into the environment, contaminating the air, soil, and local waterways. Examples of toxins that were identified in the creeks and waterways in and around Paradise included pentachlorophenol (PCP), chrysene, and polyaromatic hydrocarbons. The effects of some of these chemicals on embryonic development, hematopoiesis (blood formation), and the immune system have not been thoroughly studied. Defining safe levels and the long-term effects of exposure is imperative to understanding and mitigating potential negative future outcomes. To perform these studies, we utilized zebrafish (Danio rerio), a commonl

SUBMITTER: Namit A 

PROVIDER: S-EPMC8956169 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature