Plant AFC2 kinase desensitizes thermomorphogenesis through modulation of alternative splicing.

ABSTRACT: High ambient temperatures have adverse impacts on crop yields. Although a few plant thermosensors have been reported, these sensors directly or indirectly impact PIF4-controlled transcriptional regulation. Moreover, high temperatures also trigger a number of post-transcriptional alternative splicing events in plants and even in animals. Here, we show that LAMMER kinase AFC2 in Arabidopsis controls high-temperature-triggered alternative splicing. Plants without AFC2 exhibited distorted splicing patterns at a high ambient temperature. Further investigations revealed that high temperatures triggered alternative splicing in the majority of PIF4 target genes as a means of desensitizing PIF4 signaling. Consistently, the afc2 mutants exhibited more exaggerated high ambient temperatu

SUBMITTER: Lin J 

PROVIDER: S-EPMC8956811 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature