New insights into phenotypic heterogeneity for the distinct lipid accumulation of Schizochytrium sp. H016.

ABSTRACT:

Background

Schizochytrium sp. is a marine heterotrophic protist and an important sustainable resource for high value-added docosahexaenoic acid in the future. The production of different phenotypes during the continuous subculture of Schizochytrium sp. results in a serious reduction in lipid yield and complicates the used of this strain in scientific research and industrial production. Hence, obtaining an improved understanding of the phenotypic differences and molecular mechanisms underlying the cell-to-cell heterogeneity of Schizochytrium sp. is necessary.

Results

After continuous culture passage, Schizochytrium sp. H016 differentiated into two subpopulations with different morphologies and showed decreased capacity for lipid production. The presence of cell subpopulations

SUBMITTER: Bao Z 

PROVIDER: S-EPMC8957170 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature