The MLR, NLR, PLR and D-dimer are associated with clinical outcome in lung cancer patients treated with surgery.

ABSTRACT:

Objective

The study objective was to investigate the use of peripheral blood biomarkers as predictors of patient survival. The aim of this study was to identify the baseline peripheral blood biomarkers associated with clinical outcome in patients with early lung cancer (stage I-II) treated with surgery.

Methods

We included and analysed data from 376 patients with early-stage lung cancer who underwent a standard lobectomy. Univariate and multivariate Cox regression analyses were performed on all patients to assess the relationships between progression-free survival (PFS) and overall survival (OS) and the peripheral blood biomarker metrics measured before surgical treatment. The peripheral blood parameters included monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte r

SUBMITTER: Wang J 

PROVIDER: S-EPMC8957174 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature